BY
S. S. GUTTAL, N. P. PATIL & A. D. SHETYE Department of Prosthodontics, SDM College of Dental Sciences and
Hospital, Dharwad, Karnataka, India


Prosthetic rehabilitation of the midfacial
defects has always perplexed maxillofacial prostho-
dontists. These midfacial defects lead to functional
and cosmetic deficiencies. One of the causes of such
defects is midline lethal granuloma, which is a
destructive granulomatous lesion of uncertain ae-
tiology, involving the nose, paranasal sinuses and
the palate. Presented here is a clinical report of a 22-
year-old male patient diagnosed to have lethal
midline granuloma, who was referred to the Depart-
ment of Prosthodontics, SDM College of Dental
Sciences Dharwad. The patient had a severe mid-
facial defect involving the nose, the paranasal
sinuses, the palate and the soft tissues of the face.
Although the lesion was not of the rapidly progres-
sive type at the time of rehabilitation, the non-
specific inflammatory process was persisting. The
patient was treated with chemotherapy and pallia-
tive therapy. The primary objective of the prosthetic
rehabilitation was to provide closure of the severe
defect to protect the soft tissues from environmen-
tal exposure. Secondarily the prosthesis also pro-
vided acceptable aesthetics and psychological
benefit to the patient.

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